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93076-89-2
11aH-cyclopenta[a]phenanthren-1-yl]ethan-1-one
CD271 sodium salt
InChi: InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2
CAS Number: 51833-78-4
Topotecan Hydrochloride Size:Solid 2 mg 93076-89-2Topocecan is a semisynthetic derivative of camptothecin with antineoplastic activity. During the S phase of the cell cycle, topotecan selectively stabilizes topoisomerase I DNA covalent complexes, inhibiting religation of topoisomerase I mediated single strand DNA breaks and producing potentially lethal double strand DNA breaks when complexes are encountered by the DNA replication machinery. Camptothecin is a cytotoxic quinoline based alkaloid