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and Rispenzepine (M1/M3) on cholinergic neural contractile responses evoked by electrical field stimulation (EFS) and [3H]ACh release
exhibits LD50 and ED50 values of 142 mg and 7
Incubation of H4IIE rat hepatoma cells with Galegine hydrochloride (10 or 300 μM) for up to 6 hours produces a time-dependent activation of AMPK measured in cell lysates
CC1(C)O[C@@](CCCNC)(C2=CC=CC=C12)C1C=CC=CC=1
exhibits evident scavenging activity against both authentic ONOO- and SIN-1-derived ONOO- with IC50s of 3
SR-1114 Catalog No.:M33701-C and Rispenzepine (M1/M3) on cholinergicSR 1114 is a first in class PROTAC ENL degrader. SR 1114 elicits rapid, CRBN dependent degradation of ENL with DC50s of 150 nM, 311 nM, and 1. 65 M in MV4; 11 , MOLM 13, and OCI AML 2 cells, respectively. Product information CAS Number: 2769141 82 2 Molecular Weight: 830. 86 Formula: C39H42N8O11S Smiles: O=S(=O)(NC1=CC=CC(=C1)C1=CN2C=C(C=CC2=N1)C(=O)NC1CCC1)NCCOCCOCCNC(=O)COC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O InChiKey: WPVVPCVQEBQVLL UHFFFAOYSA N