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184(11):6529-36
Chemical Name: 4-(1-(3
2018 Feb 1
SC-514 shows a dose-dependent inhibition of TNFα production
Lower concentration (0
SB-269970 Hydrochloride - CAS# 261901-57-9 Size:Solid 2 mg 184(11):6529-36SB269970 HCl is a potent 5 HT7A antagonist (pKi = 8. 9) that demonstrates >50 fold binding selectivity over 5 HT5A and >250 fold selectivity over 5 HT1, 5 HT2, 5 HT4, 5 HT6, adrenergic 1, dopamine D2, and dopamine D3 receptors. It is also reported to block adrenergic 2 receptors in guinea pig vas deferens. SB 269970 has been used to target the 5 HT7 receptor in the study of schizophrenia like cognitive deficits. Product information CAS Number: 261901