Cyclovirobuxine D - CAS# 860-79-7 Catalog No.:M12537-10 4R)-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-yl]-2-methoxybenzamide

4R)-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-yl]-2-methoxybenzamide

as well as their proliferation

(R)-Selisistat

HIF-C2 provides an opportunity to delineate differences in HIF-1 and HIF-2 biology and serves as an entry point for development of HIF-2 inhibitor drugs for treating diseases

Valgimigli M

Cyclovirobuxine D - CAS# 860-79-7 Catalog No.:M12537-10 4R)-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-yl]-2-methoxybenzamideCyclovirobuxine D (CVB D) is the main active component of the traditional Chinese medicine Buxus microphylla. Cyclovirobuxine D induces autophagy and attenuates the phosphorylation of Akt and mTOR. Cyclovirobuxine D inhibits cell proliferation of gastric cancer cells through suppression of cell cycle progression and inducement of mitochondria mediated apoptosis. Cyclovirobuxine D is beneficial for heart failure induced by myocardial infarction.