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InChiKey: XLSYZSRXVVCHLS-UHFFFAOYSA-N
Solubility: DMSO : 100 mg/mL (246
Molecular Weight: 551
intraperitoneally injected
2 mg/kg Pipethiadene and only after the middle dose of Pizotifen malate
PF-04449913 0 Racemate InChiKey: XLSYZSRXVVCHLS-UHFFFAOYSA-NGlasdegib, also known as PF 04449913, is an orally bioavailable small molecule inhibitor of the Hedgehog (Hh) signaling pathway with potential antineoplastic activity. Hedgehog inhibitor PF 04449913 appears to inhibit Hh pathway signaling. The Hh signaling pathway plays an important role in cellular growth, differentiation and repair. Constitutive activation of Hh pathway signaling has been observed in various types of malignancies. Product