![Fenbufen R-49009 Chemical Name: N-{2-[(5-fluoro-2-{[2-methoxy-4-(morpholin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}methanesulfonamide hydrochloride](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M12707_1626682644.gif?v=1628131433)
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Chemical Name: N-{2-[(5-fluoro-2-{[2-methoxy-4-(morpholin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}methanesulfonamide hydrochloride
erythrocytes and liver with IC50 values of 10 nM
also known as ARRY-520
Chemopreventive and therapeutic effects of nimbolide in cancer: the underlying mechanisms
InChiKey: WVHMNCOFPWFUMF-UHFFFAOYSA-N
Fenbufen R-49009 Chemical Name: N-{2-[(5-fluoro-2-{[2-methoxy-4-(morpholin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}methanesulfonamide hydrochlorideFenbufen (CL 82204) is an orally active non steroidal anti inflammatory drug (NSAID), with analgetic and antipyretic effects. Fenbufen has potent activity in a variety of animal model, including carageenin edema, UV erythema and adjuvant arthritis. Fenbufen has inhibitory activities against COX 1 and COX 2 with IC50s of 3. 9 M and 8. 1 M, respectively. Fenbufen is a caspases (caspase 1, 3, 4, 5, 9) inhibitor. Product information CAS Number: 36330 85 5
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