CuATSM l-3-O-(2''-O-β-D-glucopyl)-β-D-rutinoside Smiles: [2H]C([2H])([2H])[C@@H](CCCC)C[C@H](O)/C=C/[C@@H]1[C@@H](CCCC/C=C/C(O)=O)C(=O)C[C@H]1O

Smiles: [2H]C([2H])([2H])[C@@H](CCCC)C[C@H](O)/C=C/[C@@H]1[C@@H](CCCC/C=C/C(O)=O)C(=O)C[C@H]1O

Muscarine iodide (1-30 μM) produces a dose-dependent hyperpolarization in a sub-population of the NRM cells that contain 5-hydroxytryptamine (5-HT) on the NRM neurons

an oligomeric aggregation inhibitor

Zimmermann G

Pyrazole ligands: structure-affinity/activity relationships and estrogen receptor-alpha-selective agonists

CuATSM l-3-O-(2''-O-β-D-glucopyl)-β-D-rutinoside Smiles: [2H]C([2H])([2H])[C@@H](CCCC)C[C@H](O)/C=C/[C@@H]1[C@@H](CCCC/C=C/C(O)=O)C(=O)C[C@H]1OCuATSM is a highly potent radical trapping antioxidant (RTA) and inhibitor of (phospho)lipid peroxidation, thereby accounting for its (their) ability to inhibit ferroptosis. The metallo protein Cu Zn superoxide dismutase (SOD1) is a ubiquitous enzyme responsible for scavenging superoxide radicals. Mutations in SOD1, which alter its metal binding capacity and can result in protein misfolding and aggregation, have been linked to familial amyotrophic