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SSR128129E
Dovitinib significantly reduces the basal phosphorylation levels of FGFR-1
Gründker C
Mattheyses AL
and concomitantly increased level of sphingosine-1-phosphate (S1P) precursor ceramide in AML cells
Dabrafenib Mesylate - CAS# 1195768-06-9 size:10mg solid SSR128129EDabrafenib Mesylate, CAS No. 1195768 06 9, also known as GSK2118436 , is an orally bioavailable inhibitor of B raf (BRAF) protein with potential antineoplastic activity. Dabrafenib selectively binds to and inhibits the activity of B raf, which may inhibit the proliferation of tumor cells which contain a mutated BRAF gene. B raf belongs to the the raf mil family of serine threonine protein kinases and plays a role in regulating the MAP kinase ERKs
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