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AK-7 is a good chemical probe to study SIRT2’s roles in metabolic diseases
IDO5L and IDO-IN-2 with CAS#914471-09-3
AMD-3465 (50 nM) totally blocks CXCL12-induced calcium mobilization
Therapeutic potential of AZD1480 for the treatment of human glioblastoma
KL001 serves as a useful tool to study the regulation of CRY-dependent physiology and may help development of clock-based therapeutics for treating diabetes
Verteporfin (Visudyne) - YAP Inhibitor. CAS# 129497-78-5 045 AK-7 is a good chemicalVerteporfin (Visudyne), CAS No. 129497 78 5, is a potent and selective YAP inhibitor, disrupts YAP TEAD interactions and enhances trypsin cleavage of YAP with EC50 ~100 nM. It inhibits growth and proliferation of retinoblastoma cells. It also significantly blocks cancer stem cell (CSC) properties in cells with high YAP1 and a high proportion of ALDH1(+). In vivo it can suppress YAP induced liver overgrowth in mice. Product information CAS Number: