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PIP4K-IN-a131 is PIP4K lipid kinases inhibitor
) alleviates D-GalN induced hepatotoxicity in mice
CAS Number: 1403859-14-2
Solubility: DMSO : ≥ 25 mg/mL (64
22(4):537-50
PF-3450074 60276 PIP4K-IN-a131 is PIP4K lipid kinasesPF 3450074 (PF 74) is a specifical inhibitor of HIV 1 capsid protein (CA) and displays a broad spectrum inhibition of HIV isolates with submicromolar potency (EC50=8 640 nM). PF 3450074 (PF 74) acts at an early stage of HIV 1 infection, inhibits viral replication by directly competing with the binding of CPSF6 and NUP153, and blocks the uncoating, assembly, and the reverse transcription steps of the viral life cycle. CPSF6: nuclear host factors
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