Maleimide-DOTA RAK inhibitor 4 (trans) Chemical Name: 5-[[15a-[2-[[1-[[4-amino-1-[2-[[1-[[6-amino-1-[[2-[2-[[1-[(1-carboxy-2-hydroxypropyl)amino]-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-1-oxohexan-2-yl]amino]-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-1

Chemical Name: 5-[[15a-[2-[[1-[[4-amino-1-[2-[[1-[[6-amino-1-[[2-[2-[[1-[(1-carboxy-2-hydroxypropyl)amino]-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-1-oxohexan-2-yl]amino]-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-1

Formula: C19H21F3N6

PubMed Central PMCID: PMC4421799

Solubility: DMSO : ≥ 100 mg/mL (274

GNE-0877 is a highly potent and selective LRRK2 inhibitor

Maleimide-DOTA RAK inhibitor 4 (trans) Chemical Name: 5-[[15a-[2-[[1-[[4-amino-1-[2-[[1-[[6-amino-1-[[2-[2-[[1-[(1-carboxy-2-hydroxypropyl)amino]-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-1-oxohexan-2-yl]amino]-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-1Maleimide DOTA is a non cleavable ADC linker used in the synthesis of antibody drug conjugates (ADCs). Product information CAS Number: 1006711 90 5 Molecular Weight: 526. 54 Formula: C22H34N6O9 Chemical Name: 2 [4,7 bis(carboxymethyl) 10 ({[2 (2,5 dioxo 2,5 dihydro 1H pyrrol 1 yl)ethyl]carbamoyl}methyl) 1,4,7,10 tetraazacyclododecan 1 yl]acetic acid Smiles: OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCN2C(=O)C=CC2=O)CCN(CC(O)=O)CC1 InChiKey: AUTDIWAXETZSGJ