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BKM-120 hydrochloride
indicating that NHC-TP competes predominantly with CTP for incorporation
48 hours) may exerts its apoptotic effects by regulating the apoptotic proteins and the IAP family of proteins in A549 and H460 cells
a Topoisomerase II Targeting Agent with Cellular Selectivity for the Topoisomerase IIα Isoform
5-trihydroxy-6-{[2-(4-hydroxyphenyl)-3-{4-[2-(piperidin-1-yl)ethoxy]benzoyl}-1-benzothiophen-6-yl]oxy}oxane-2-carboxylic acid
W-54011 Catalog No.:M20237-C BKM-120 hydrochlorideW 54011 is a potent and orally active non peptide C5a receptor antagonist. W 54011 inhibits the binding of 125I labeled C5a to human neutrophils with a Ki value of 2. 2 nM. W 54011 also inhibits C5a induced intracellular Ca2+ mobilization, chemotaxis, and generation of ROS in human neutrophils with IC50s of 3. 1 nM, 2. 7 nM, and 1. 6 nM, respectively. Product information CAS Number: 405098 33 1 Molecular Weight: 493. 08 Formula: C30H37ClN2O2 Chemical
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