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Purmorphamine - Hedgehog Agonist. CAS# 483367-10-8 66046 11-12H2/t15-/m0/s1

SKU: 39266641681

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Description

11-12H2/t15-/m0/s1

It has no significant activity against a panel of 260 kinases at concentrations up to 10 µM

Kunisada Y

D-alpha-Hydroxyglutaric acid disodium

(2014) Nat Commun

Purmorphamine - Hedgehog Agonist. CAS# 483367-10-8 66046 11-12H2/t15-/m0/s1Purmorphamine, CAS No. 483367 10 8, is a Hedgehog agonist, which activates the Hedgehog pathway by targeting Smoothened. Purmorphamine induces osteogenesis by activation of the hedgehog signaling pathway. Purmorphamine increases DARPP 32 differentiation in human striatal neural stem cells through the Hedgehog pathway. Purmorphamine enhances osteogenic activity of human osteoblasts derived from bone marrow mesenchymal cells. Hedgehog (Hh) signaling is

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