Tirapazamine 0577 Smiles: CC(C)C[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CS)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCSC)NC=O)C(O)=O

Smiles: CC(C)C[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CS)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCSC)NC=O)C(O)=O

blocks the effects of stronger agents with greater intrinsic activity such as morphine whilst simultaneously producing analgesia

It binds EGFR without inducing degradation

InChiKey: MLSVJHOYXJGGTR-UHFFFAOYSA-N

Goodwin NC

Tirapazamine 0577 Smiles: CC(C)C[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CS)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCSC)NC=O)C(O)=OTrapazamine, also known as SR 4233,DNA damaging drug potentially for the treatment of cervical carcinoma, head and neck cancer. Tirapazamine is activated to its toxic form preferentially in the hypoxic areas of solid tumors. Cells in these regions are resistant to killing by radiotherapy and most anticancer drugs. Thus the combination of tirapazamine with conventional anticancer treatments is particularly effective. Product information CAS Number: