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Ficarro SB
RG7800 is shown to promote the inclusion of exon 7 in SMN2 mRNA
InChi: InChI=1S/C18H18FN3OS/c1-2-21(14-8-6-12(19)7-9-14)11-13-10-17(23)22-15-4-3-5-16(15)24-18(22)20-13/h6-10H
InChi: InChI=1S/C23H21N5O/c24-22(29)18-11-12-19-26-20(21(28(19)27-18)16-5-2-1-3-6-16)15-7-9-17(10-8-15)23(25)13-4-14-23/h1-3
CAS Number: 2095832-33-8
ARM1 entiobiosiden Ficarro SBARM1 (4 (4 benzylphenyl) thiazol 2 amine) is a LTB4 synthesis inhibitor . Leukotriene A4 (LTA4) hydrolase aminopeptidase is a bifunctional zinc metalloenzyme that catalyzes the synthesis of the proinflammatory mediator LTB4 from LTA4 and cleaves the chemotactic tripeptide Pro Gly Pro. LTB4 is a key lipid mediator in the innate immune response . ARM1 is a LTB4 synthesis inhibitor. ARM1 is a thiazolamine that inhibits LTB4 synthesis and conversion of
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