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with SERT-binding and radioisotope activities
Chemical Name: N-(26-azido-3
and MAP4K5 with IC50s of 20
Mcl-1 inhibitor 6 shows ideal selectivity against CML cell line K562 (IC50>30 μM)
Smiles: CCCCN1C(=O)[C@H](NC(=O)C21CCN(CC1C=CC(=CC=1)OC1=CC=C(C=C1)C(O)=O)CC2)[C@H](O)C1CCCCC1
(S)-CCG-1423 Catalog No.:M23385-C with SERT-binding and radioisotope activities(S) CCG 1423 is a stereoisomer of CCG 1423. CCG 1423 is a Rho inhibitor involved in blocking signaling through myocardin related transcription factor A (MRTF A) and serum response factor (SRF) . The Rho family of small GTPases plays an important role in cancer metastasis. Up regulation of RhoA or RhoC has been associated with a poor clinical outcome. Rho GTPases are important for the actin cytoskeleton. The RhoA family plays an important role in