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RAGE antagonist peptide TFA is an advanced glycation end products (RAGE) antagonist
which is an angiotensin converting enzyme (ACE) inhibitor
Solubility: DMSO : 125 mg/mL (352
12(1):53-61
GSK2981278
CpdA Size:Contact [email protected] for quotation RAGE antagonist peptide TFA isCpdA is a non steroidal selective glucocorticoid receptor modulator. It is an aziridine precursor that can infiltrate cells and is translocated to the nucleus. It inhibits glucocorticoid receptor dimerization, which prevents transcription of gene targets such as NF B and subsequent cytokines through transrepression. Studies have shown contradictory results for binding affinity of CpdA compared with dexamethasone that were either higher (4 fold, IC50 =