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Smiles: OC(=O)COC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O
histologic type
Degenhardt T
is active in inducing apoptosis in tumor cells without affecting normal cells
Perelson AS
O-Desmethyl gefitinib - CAS# 847949-49-9 182AM7 E Smiles: OC(=O)COC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=OO Desmethyl gefitinib is an active metabolite of Gefitinib in human plasma. The formation of O desmethyl gefitinib is dependent on CYP2D6 activity. O desmethyl gefitinib inhibits EGFR with an IC50 of 36 nM in subcellular assays. Product information CAS Number: 847949 49 9 Molecular Weight: 432. 88 Formula: C21H22ClFN4O3 Chemical Name: 4 [(3 chloro 4 fluorophenyl)amino] 6 [3 (morpholin 4 yl)propoxy]quinazolin 7 ol Smiles:
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