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also known as MPV-785
SCHEMBL1971868
Effects of the antitussive drug cloperastine on ventricular repolarization in halothane-anesthetized guinea pigs
(2010) Nat Biotechnol
is a potent inhibitor of class I PI3K kinases with an IC50 of 19 nM
PAP-1 ethylcarbamazine citrate also known as MPV-785SPS 4251, also known as AS 77 and PAP 1, is a KCNA3 (Potassium voltage gated channel, shaker related subfamily, member 3) channel blocker potentially for the treatment of plaque psoriasis. Kv1. 3 channels regulate the activation proliferation of effector memory T cells and thus play a critical role in the pathogenesis of autoimmune diseases. PAP 1 reduced the secretion of TNF by adipose tissue but had no effect on the secretion of IL 6. PAP 1 can also
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