Propargyl-PEG4-acid Size:Contact [email protected] for quotation 57(5):2033-46

57(5):2033-46

CC1C2=C(SC=1C(=O)NCCCCCNC1=CC=CC3=C1C(=O)N(C1CCC(=O)NC1=O)C3=O)N1C(=NN=C1C)[C@H](CC(=O)OC)N=C2C1C=CC(Cl)=CC=1

Fluvastatin sodium (XU 62320) is a first fully synthetic

2R)-1-hydroxy-1-phenylpropan-2-yl]carbamoyl}-1-methoxy-2-methylethyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl](methyl)carbamoyl}-2-methylpropyl]carbamoyl}-2-methylpropyl]-N-methylhexanamide

2001 Feb 23

Propargyl-PEG4-acid Size:Contact [email protected] for quotation 57(5):2033-46Propargyl PEG4 acid is a PEG based PROTAC linker can be used in the synthesis of BTK IAP PROTACs Ibrutinib (HY 10997) based PROTAC 2 and an analogue PROTAC 3. PROTAC 3 causes BTK degradation with a DC50 of 200 nM in THP 1 cells. Product information CAS Number: 1415800 32 6 Molecular Weight: 260. 28 Formula: C12H20O6 Chemical Name: 4,7,10,13 tetraoxahexadec 15 ynoic acid Smiles: C#CCOCCOCCOCCOCCC(O)=O InChiKey: WMBXAUWIPBFEOK UHFFFAOYSA N InChi: