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ML264 efficiently inhibits the rate of proliferation of both cell lines
1951408-58-4
0 μM) and cytotoxic activity on K562 cancer cells (IC50=6
AMG-548 has an modest selectivity against JNK2 (ki=39 nM) and JNK3 (ki=61 nM)
The most differentiating components are the head of the inhibitor and the lack of a methyl substituent on ring A
rac-N, N-Didesmethyl-N-(4-hydroxyphenethyl)-O-desmethyl Venlafaxine-d11 Catalog No.:M23478-C ML264 efficiently inhibits the rateProduct information CAS Number: 1346598 87 5 Molecular Weight: 366. 54 Formula: C22H29NO3 Chemical Name: 4 [2 ({2 [1 hydroxy(2,2,3,3,4,4,5,5,6,6 H)cyclohexyl] 2 (4 hydroxyphenyl)(2 H)ethyl}amino)ethyl]phenol Smiles: [2H]C(CNCCC1C=CC(O)=CC=1)(C1C=CC(O)=CC=1)C1(O)C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C1([2H])[2H] InChiKey: UMYJDHWHTKQULQ AQUQGOPSSA N InChi: InChI=1S C22H29NO3 c24 19 8 4 17(5 9 19)12 15 23 16 21(18 6 10 20(25)11 7