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CAS Number: 313967-18-9
Oral Aticaprant (CERC-501) administration selectively and potently occupies central kappa opioid receptors (ED50=0
AUY-922 (500 nM) in combination with NSC 118218 more effectively induces apoptosis in cells in co-culture than either drug alone
a tertiary alkaloid with anticholinesterase and neurocognitive-enhancing activities
for 3 or 4 days) has potent anti-proliferative effects on MCL cell lines
PF-3845 RB597 CAS Number: 313967-18-9PF 3845 is a fatty acid amide hydrolase (FAAH) inhibitor, and acts in the nervous system to reverse LPS induced tactile allodynia in mice. PF 3845 promotes neuronal survival, attenuates inflammation and improves functional recovery in mice with traumatic brain injury. Treatment with PF3845 inactivated FAAH activity and enhanced the AEA levels in the brain. It reduced neurodegeneration in the dentate gyrus, and up regulated the expression of Bcl 2 and