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In NOD mice
a thienopyridine and prodrug
CAS Number: 1356962-20-3
PDE4B-IN-2 is an orally active and selective PDE4B inhibitor (IC50=15 nM) and exhibits >100-fold selectivity for PDE4B over 4D
as assessed by hematoxylin and eosin and anti-K14 histological staining at the study end
PTP Inhibitor IV - CAS# 329317-98-8 Catalog No.:M23057-C In NOD miceIC50: 1. 8, 2. 5, 8. 4, 13, 20, 6. 4, and 6. 7 M for SHP 2, PTP1B, PTP , PTP Meg 2, PTP , PTP , and PTP , respectively PTP Inhibitor IV is a protein tyrosine phosphatases (PTPs) inhibitor. PTPs are reported to be important in the regulation of various signal transduction processes. Enzymes of this class are considered as potential therapeutic targets in the treatment of various diseases including inflammation, diabetes, as well as cancer. However,
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