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PROTAC MDM2 Degrader-2 statin D6 Sodium Robust induction of both BSEP

SKU: 43723671212

4.6
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Description

Robust induction of both BSEP and SHP genes is observed in primary cells by Tropifexor in a concentration-dependent manner

Testing of INCB024360-analog in mice demonstrated pharmacodynamic inhibition of IDO

SR0987 clearly shows a concentration dependent induction of reporter gene expression with an EC50 of ~800nM

although cell viability is not affected

5E)-1-benzyl-3

PROTAC MDM2 Degrader-2 statin D6 Sodium Robust induction of both BSEPPROTAC MDM2 Degrader 2 is a MDM2 degrader based on PROTAC technology. PROTAC MDM2 Degrader 2 composes of a potent MDM2 inhibitor, linker, and the MDM2 ligand for E3 ubiquitin ligase. Product information CAS Number: 2249944 99 6 Molecular Weight: 1391. 22 Formula: C70H76Cl4N10O12 Chemical Name: 2 {4 [(4R,5S) 4,5 bis(4 chlorophenyl) 2 [4 methoxy 2 (propan 2 yloxy)phenyl] 4,5 dihydro 1H imidazole 1 carbonyl] 2 oxopiperazin 1 yl} N (2 {2 [2 (2 {4 [(4R,5S)

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