Enzastaurin - CAS# 170364-57-5 0280 or growth inhibition of established

or growth inhibition of established M229R and 1205LuR xenografts in SCID mice

957054-33-0 (mesylate)

15(1):23-36

autophosphorylates and initiates splicing of XBP1 mRNA

CAS Number: 457961-34-1

Enzastaurin - CAS# 170364-57-5 0280 or growth inhibition of establishedEnzastaurin, CAS No. 170364 57 5, also known as DB 102 and LY317615, is a synthetic macrocyclic bisindolemaleimide with potential antineoplastic activity. Binding to the ATP binding site, enzastaurin selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF) stimulated neo angiogenesis. This agent may decrease tumor blood supply and so tumor burden. Product information CAS Number: