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Formula: C8H14ClN5O4
PPARδ (30
CAS Number: 150399-21-6
Solubility: DMSO : ≥ 60 mg/mL (138
The Quassin treated rats has a significantly decreased mean litter number and weight
AZD 5153 Catalog No.:M22444-C Formula: C8H14ClN5O4Target: BRD4 IC50: 5 nM AZD5153 is a potent, selective, and orally available inhibitor of the bromodomain and extraterminal (BET) protein BRD4, with the IC50 value of 5 nM. AZD5153 could simultaneously ligate two bromodomains in BRD4, and exert antitumor activity in multiple xenograft tumor models . In Vitro: A quantitative immuno fluorescent assay in U2OS cells revealed that AZD5153 could significantly disrupt BRD4 foci, with the IC50 value of 1. 7