BIO-32546 facitinib Smiles: CCC1=NC2=C(C=C(C)N=C2C)N1C1=CC=C(CCNC(=O)NS(=O)(=O)C2C=CC(C)=CC=2)C=C1

Smiles: CCC1=NC2=C(C=C(C)N=C2C)N1C1=CC=C(CCNC(=O)NS(=O)(=O)C2C=CC(C)=CC=2)C=C1

Smiles: [O-][N+](=O)C1=CN2C[C@@H](COC2=N1)OCC1C=NC(=CC=1)C1C=CC(=CC=1)OC(F)(F)F

CAS Number: 5578-73-4

Following treatment with Brusatol (NSC 172924) and CDDP for 48 h

CAS Number: 174671-46-6

BIO-32546 facitinib Smiles: CCC1=NC2=C(C=C(C)N=C2C)N1C1=CC=C(CCNC(=O)NS(=O)(=O)C2C=CC(C)=CC=2)C=C1BIO 32546 (example 12b, S isomer) is an autotaxin (ATX) modulator, extracted from the patent US20170158687A1. Product information CAS Number: 1548743 66 3 Molecular Weight: 543. 54 Formula: C28H31F6NO3 Chemical Name: 8 [(1S) 1 (7 {[(1s,4s) 4 (trifluoromethyl)cyclohexyl]oxy} 8 (trifluoromethyl)naphthalen 2 yl)ethyl] 8 azabicyclo[3. 2. 1]octane 3 carboxylic acid Smiles: