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MDL 28170 is a calpain inhibitor that protects against cortical neuronal damage even if the treatment is delayed until 3 h after reperfusion
RCGD423 is a gp130 modulator
CAS Number: 1189957-99-0
9-dichloro-1H
6-²H₅)benzoyl]-4-chloroaniline
CHMFL-EGFR-202 Size:Contact [email protected] for quotation MDL 28170 is a calpainCHMFL EGFR 202 is a potent, irreversible inhibitor of epidermal growth factor receptor (EGFR) mutant kinase, with IC50s of 5. 3 nM and 8. 3 nM for drug resistant mutant EGFR T790M and WT EGFR kinases, respectively. CHMFL EGFR 202 exhibits 10 fold selectivity for EGFR L858R T790M against the EGFR wild type in cells. CHMFL EGFR 202 adopts a covalent DFG in C helix out inactive binding conformation with EGFR, with strong antiproliferative effects against
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