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N-Desethyl Sunitinib Size:Solid 10 mg CAS Number: 81403-80-7

SKU: 46138915236

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Description

CAS Number: 81403-80-7

Formula: C21H22O11

Risperidone mesylate(R 64 766 mesylate) is a serotonin 5-HT2 receptor blocker

Richard Woessner

Desbutyl Lumefantrine D9 is the deuterium labeled euterium labeled

N-Desethyl Sunitinib Size:Solid 10 mg CAS Number: 81403-80-7N Desethyl Sunitinib is a metabolite of sunitinib. Sunitinib is a potent, ATP competitive VEGFR, PDGFR and KIT inhibitor with Ki values of 2, 9, 17, 8 and 4 nM for VEGFR 1, 2, 3, PDGFR and KIT, respectively. Sunitinib also potently inhibits Kit and FLT 3. Sunitinib inhibits VEGF induced proliferation of serum starved HUVECs with IC50 of 40 nM, and inhibits PDGF induced proliferation of NIH 3T3 cells overexpressing PDGFR or PDGFR with IC50 of 39 nM and

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