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478688-75-4 (trans&cis)
Chemical Name: N-{4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-3-[(E)-2-{4-methoxy-1H-pyrrolo[2
5-{[(3Z)-5-fluoro-2-oxo-2
preventing the phosphorylation and activation of STATs
Treatment of AML cell lines (MV4-11 and THP-1) and primary blasts with HLCL-61 also results in a decrease of cell viability
AZ-3 60246 478688-75-4 (trans&cis)AZ 3 is a potent and selective JAK1 inhibitor with an IC50 of 34 nM. Product information CAS Number: 2228908 91 4 Molecular Weight: 385. 48 Formula: C20H28FN7 Chemical Name: N4 [(2R) butan 2 yl] N2 {2 fluoro 5 [(1S, 4S) 5 methyl 2, 5 diazabicyclo[2. 2. 1]heptan 2 yl]pyridin 3 yl} 5 methylpyrimidine 2, 4 diamine Smiles: CN1C[C@@H]2C[C@H]1CN2C1=CN=C(F)C(=C1)NC1=NC(N[C@H](C)CC)=C(C)C=N1 InChiKey: UPSHDXGMMFOWPL KBMXLJTQSA N InChi: InChI=1S C20H28FN7 c1 5
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