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InChi: InChI=1S/C22H25N3O4/c26-18-4-1-5-19(28-11-13-6-7-13)20(18)17-9-15(14-3-2-8-23-10-14)16-12-29-22(27)25-21(16)24-17/h1
NSC 669364
10-diazatricyclo[6
3-thiazol-2-yl)benzene-1-sulfonamide
meaning that aloin-containing products are no longer available in over-the-counter drug products in the United States
VX-661 Catalog No.:M10067-10 InChi: InChI=1S/C22H25N3O4/c26-18-4-1-5-19(28-11-13-6-7-13)20(18)17-9-15(14-3-2-8-23-10-14)16-12-29-22(27)25-21(16)24-17/h1Tezacaftor, also known asVX 661, is CFTR modulator. VX 661 is potentially useful for treatment of cystic fibrosis disease. Cystic fibrosis (CF) is a genetic disease caused by defects in the CF transmembrane regulator (CFTR) gene, which encodes an epithelial chloride channel. The most common mutation, 508CFTR, produces a protein that is misfolded and does not reach the cell membrane. VX 661 can correct trafficking of 508CFTR and partially restore
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