A-836339 60106 0]oct-2-en-7-ylamino)-2-amino-6-oxohexanoate

0]oct-2-en-7-ylamino)-2-amino-6-oxohexanoate

potent and selective inhibitor of the deubiquitinylating enzymes (DUBs)

is a well-known representative of naturally polyether ionophore antibiotics

as well as the expression of a range of other Hif-1α-dependent genes

Formula: C55H84N17O21S3

A-836339 60106 0]oct-2-en-7-ylamino)-2-amino-6-oxohexanoateA 836339 is a drug developed by Abbott Laboratories that acts as a potent cannabinoid receptor full agonist. It is selective for CB2, with Ki values of 0. 64 nM at CB2 vs 270 nM at the psychoactive CB1 receptor, but while it exhibits selective analgesic, anti inflammatory and anti hyperalgesic effects at low doses, its high efficacy at both targets results in typical cannabis like effects appearing at higher doses, despite its low binding affinity for