Lenalidomide-C5-NH2 362450 Flavopiridol exhibits potent cytotoxicity against

Flavopiridol exhibits potent cytotoxicity against a wide variety of tumor cell lines with IC50 values ranging form 16 nM for LNCAP to 130 nM for K562

51(25):6140-6143 [2]

REH (IC50: 13

2014 Mar 1

Fleroxacin (Ro 23-6240)

Lenalidomide-C5-NH2 362450 Flavopiridol exhibits potent cytotoxicity againstLenalidomide C5 NH2 is the Lenalidomide based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide C5 NH2 can be connected to the ligand for protein by a linker to form PROTAC, such as MDM2 PROTAC degrader. Product information CAS Number: 2093388 45 3 Molecular Weight: 329. 39 Formula: C18H23N3O3 Chemical Name: 3 [4 (5 aminopentyl) 1 oxo 2,3 dihydro 1H isoindol 2 yl]piperidine 2,6 dione Smiles: NCCCCCC1=CC=CC2=C1CN(C1CCC(=O)NC1=O)C2=O