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K145 - CAS# 1309444-75-4 Size:Solid 2 mg CAS Number: 84176-65-8

SKU: 47319848981

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Description

CAS Number: 84176-65-8

Epub 2014 Apr 23

Dirithromycin is a macrolide glycopeptide antibiotic

Target: D1 ReceptorFenoldopam is a selective dopamine-1 (DA1) agonist with natriuretic/diuretic properties

Epub 2015 Sep 16

K145 - CAS# 1309444-75-4 Size:Solid 2 mg CAS Number: 84176-65-8K145 is a selective sphingosine kinase 2 (SphK2) inhibitor and anticancer agent. K145 inhibited the activity of SphK2 in a dose dependent manner with an IC50 of 4. 300. 06 M. K145 also exhibited inhibitory effects on the growth of U937 cells as well as apoptotic effects in U937 cells. K145 exhibits comparable in vivo anti tumor activity to tamibarotene, while concomitantly exhibiting less toxicity in this U937 xenograft cancer model. Product

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