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5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide
SB-525334 (1 microM) blocked TGF-beta1-induced phosphorylation and nuclear translocation of Smad2/3 in renal proximal tubule cells and inhibited TGF-beta1-induced increases in plasminogen activator inhibitor-1 (PAI-1) and procollagen alpha1(I) mRNA expression in A498 renal epithelial carcinoma cells
PubMed PMID: 19671025
InChi: InChI=1S/C19H20N6O6/c20-24-22-9-2-1-8-21-15(27)10-31-13-5-3-4-11-16(13)19(30)25(18(11)29)12-6-7-14(26)23-17(12)28/h3-5
Molecular Weight: 492
Tabersonine 3030 5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamideTabersonine is an indole alkaloid mainly isolated from Catharanthus roseus. Tabersonine disrupts A(1 42) aggregation and ameliorates A aggregate induced cytotoxicity. Tabersonine has anti inflammatory activities and acts as a potential therapeutic candidate for the treatment of ALI ARDS. Product information CAS Number: 4429 63 4 Molecular Weight: 336. 43 Formula: C21H24N2O2 Chemical Name: methyl (1R,12R,19S) 12 ethyl 19 hydrogenio 8,16