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Exploiting an allosteric binding site of PRMT3 yields potent and selective inhibitors
2S)-1-{[1-(4-fluorophenyl)-1H-indazol-5-yl]oxy}-1-(3-metho xyphenyl)-2-propanyl]acetamide (AZD-5423)
InChi: InChI=1S/C27H36N4O5S/c1-6-37(34
Chemical Name: 7-(2
Chemical Name: 2-(3-fluoro-4-hydroxyphenyl)-7-vinylbenzo[d]oxazol-5-ol
Pizotifen Malate n (trihydrate) Exploiting an allosteric binding sitePizotifen, also known as Pizotyline, is a benzocycloheptene based drug used as a medicine, primarily as a preventative to reduce the frequency of recurrent migraine headaches. Pizotifen is a serotonin antagonist acting mainly at the 5 HT2A and 5HT2C receptors. It also has some activity as an antihistamine as well as some anticholinergic activity. Product information CAS Number: 5189 11 7 Molecular Weight: 429. 53 Formula: C23H27NO5S Synonym:
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