Pay in 4 interest-free payments of $26.25 Learn more
Ships within 48 hours · Estimated delivery Aug 22 - Aug 27
Meagher EA
Smiles: COC1=CC=CC=C1S(=O)(=O)NC1=CC2CN(C)C(=O)NC=2C=C1
LY294002 was used at 10-50 µM final concentration in various in vitro assays
Epub 2013 Mar 14
and 10 (IC50 > 100 µM)
S1RA Size:Solid 10 mg Meagher EAE 52862, also known as S1RA and MR390, is a selective sigma 1 receptor antagonist, with a reported binding affinity of Ki = 17. 0 7. 0 nM, selective over the sigma 2 receptor and against a panel of other 170 receptors, enzymes, transporters and ion channels. In preclinical studies, S1RA has demonstrated efficacy in relieving neuropathic pain and pain in other sensitizing conditions, associated with an improvement of the emotional negative state. E