CCG-63802 - CAS# 620112-78-9 Catalog No.:M10963-2 CAS Number: 1258861-20-9

CAS Number: 1258861-20-9

and Mannhemia

1186/s12974-015-0363-z

6R)-4-amino-3

Aqueous extract of peanut skin and its main constituent procyanidin A1 suppress serum IgE and IgG1 levels in mice-immunized with ovalbumin

CCG-63802 - CAS# 620112-78-9 Catalog No.:M10963-2 CAS Number: 1258861-20-9CCG 63802 is a potent and reversible inhibitor of RGS protein. CCG 63802 inhibits the interaction between RGS4 and Galpha(o) with an IC(50) value in the low micromolar range. CCG 63802 shows selectivity among RGS proteins with a potency order of RGS 4 > 19 = 16 > 8 >> 7. CCG 63802 inhibits the GTPase accelerating protein activity of RGS4, and thermal stability studies demonstrate binding to the RGS but not to Galpha(o). CCG 63802 represents a useful