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selective and orally bioavailable Porcupine inhibitor (Wnt signaling antagonist) with an IC50 ~0
E-7449 (100 mg/kg
InChi: InChI=1S/C20H14F2N4/c21-13-5-9-15(10-6-13)23-19-20(24-16-11-7-14(22)8-12-16)26-18-4-2-1-3-17(18)25-19/h1-12H
H2O/c1-3-4-5-7-10(2)8-6-9(11
In the intact platelet
PARP-IN-1 - CAS# 3544-24-9 astatin Calcium selective and orally bioavailable Porcupine3 Aminobenzamide (3 ABA , 3 Amino Benzamide, 3 AB) is a potent inhibitor of Poly(ADP ribose)polymerase (PARP) and inhibits cell apoptosis after SCI (Spinal Cord Injury) in caspase independent way. Product information CAS Number: 3544 24 9 Molecular Weight: 136. 15 Formula: C7H8N2O Synonym: 3 Aminobenzamide INO1001 INO 1001 Chemical Name: 3 aminobenzamide Smiles: NC1C=CC=C(C=1)C(N)=O InChiKey: GSCPDZHWVNUUFI UHFFFAOYSA N InChi: InChI=1S C7H8N2O c8 6 3
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