Pay in 4 interest-free payments of $25.00 Learn more
Ships within 48 hours · Estimated delivery Aug 6 - Aug 11
Pralsetinib (BLU-667) potently inhibits growth of NSCLC and thyroid cancer xenografts driven by various RET mutations and fusions without inhibiting vascular endothelial growth factor receptor 2 (VEGFR-2)
Smiles: CC(C)(OC1C=CC(=CC=1)NC(=O)NC1C=CC(CC2C=C(Cl)C(=CC=2)NC(=O)NC2C=CC(=CC=2)OC(C)(C)C(O)=O)=CC=1Cl)C(O)=O
Micromolar concentrations of Cediranib are needed to prevent tumor cell proliferation in vitro
Tigloylgomisin P displays weak cytotoxicity against A549 cells (GI50=18
both of which can be up-regulated by β-catenin
Mirtazapine-d3 N-Oxide dene-2-ethanamine-d9 hydrobromide Pralsetinib (BLU-667) potently inhibits growthProduct information CAS Number: 1219155 54 0 Molecular Weight: 284. 37 Formula: C17H19N3O Chemical Name: 5 (H)methyl 2,5,19 triazatetracyclo[13. 4. 0. 0,. 0,]nonadeca 1(19),8,10,12,15,17 hexaen 5 ium 5 olate Smiles: [2H]C([2H])([2H])[N+]1([O ])CC2C3=CC=CC=C3CC3=CC=CN=C3N2CC1 InChiKey: GAFCUVMEBFTFQJ FIBGUPNXSA N InChi: InChI=1S C17H19N3O c1 20(21)10 9 19 16(12 20)15 7 3 2 5 13(15)11 14 6 4 8 18 17(14)19 h2 8,16H,9 12H2,1H3 i1D3 Technical Data