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InChiKey: CEIJFEGBUDEYSX-FZDBZEDMSA-N
and this pathway might be a possible therapeutic target in cardiac fibrosis
Icaritin shows potent anti-leukemia activity on chronic myeloid leukemia in vitro and in vivo by regulating MAPK/ERK/JNK and JAK2/STAT3 /AKT signalings
Formula: C23H43N3O5
InChi: InChI=1S/C20H27NO3/c1-18-7-6-14-12(13(18)3-4-15(18)22)5-8-20-17(24-20)16(23)11(10-21)9-19(14
AHU-377 - CAS# 149709-62-6 thscopolamine Bromide InChiKey: CEIJFEGBUDEYSX-FZDBZEDMSA-NSacubitril, also known as AHU377, is angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure. Sacubitril is a prodrug that is activated to LBQ657 by de ethylation via esterases. LBQ657 inhibits the enzyme neprilysin, which is responsible for the degradation of atrial and brain natriuretic peptide, two blood pressure lowering peptides that work mainly by reducing blood volume. Product information
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