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O=C1CN2[C@@H]3CC1C[C@H]2CC(C3)OC(=O)C1=CNC2=CC=CC=C12
13-tetraene-10-carboxylate
Ca/c2*1-3-5-11(24)22-16-13-17(20-8-19-16)23(9-21-13)18-15(30-12(25)6-4-2)14-10(29-18)7-28-32(26
lodoxamide inhibits compound 48/80-induced histamine release and ionophore-induced 45Ca influx with associated histamine release in purified rat peritoneal mast cells[1]
57% of viruses with genotypes containing Y181C as a single NNRTI mutation (43% for efavirenz)
XMD8-92 mterene O=C1CN2[C@@H]3CC1C[C@H]2CC(C3)OC(=O)C1=CNC2=CC=CC=C12XMD8 92 is an ERK5 BMK1 inhibitor and also BRD4 inhibitor. XMD8 92 inhibits pancreatic tumor xenograft growth via a DCLK1 dependent mechanism. XMD8 92 blocks cellular BMK1 activation and significantly suppresses tumor growth in lung and cervical tumor models and is well tolerated in animals. Product information CAS Number: 1234480 50 2 Molecular Weight: 474. 55 Formula: C26H30N6O3 Chemical Name: 5 {[2 ethoxy 4 (4 hydroxypiperidin 1 yl)phenyl]amino}