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InChi: InChI=1S/C17H16Cl3F3N2O3S/c1-25(2)5-6-28-15-9-11(3-4-12(15)18)24-29(26
stimulates IFN signals in mice
Lutein dimyristate possesses pro-oxidant activity
leading to the hypothesis that these activators interact with GTPases bind to an allosteric binding site localized between switch regions I and II
CAS Number: 568-72-9
Org 25543 hydrochloride ine trihydrochloride InChi: InChI=1S/C17H16Cl3F3N2O3S/c1-25(2)5-6-28-15-9-11(3-4-12(15)18)24-29(26IC50: 16 nM Org 25543 hydrochloride is a potent and selective glycine transporter type 2 (GlyT2) inhibitor for hGlyT2. Two major subtypes of glycine transporter are type 1 (GlyT 1) and type 2 (GlyT 2) revealed by molecular cloning. The GlyT 2 transporter has a similar distribution to ssGlyR with being confined to the spinal cord and brain stem, whereas the GlyT 1 transporter has a wide distribution throughout the CNS. In vitro: Org 25543 was
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