GNE-049 at mesylate InChi: InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7

InChi: InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7

11S)-11-hydroxy-9-methyl-3-oxatricyclo[5

ROS production

CAS Number: 943344-58-9

including cardiac troponin I (CTNI) and cardiac myosin heavy chain bright cells (MYHhi +)

GNE-049 at mesylate InChi: InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7GNE 049 is a highly potent and selective CBP inhibitor with an IC50 of 1. 1 nM in TR FRET assay. GNE 049 also inhibits BRET and BRD4(1) with IC50s of 12 nM and 4200 nM, respectively. Product information CAS Number: 1936421 41 8 Molecular Weight: 510. 58 Formula: C27H32F2N6O2 Chemical Name: 1 {3 [7 (difluoromethyl) 6 (1 methyl 1H pyrazol 4 yl) 1,2,3,4 tetrahydroquinolin 1 yl] 1 (oxan 4 yl) 1H,4H,5H,6H,7H pyrazolo[4,3 c]pyridin 5 yl}ethan 1 one Smiles: