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EPZ-6438 was orally dosed to mice at 250-500 mg/kg twice per day for 21-28 days
NS-398 suppresses writhing reactions induced by acetic acid with an ED50 of 8
48% of the total agonist response
29 μM) is about 10 times weaker than that for human H4R
5-HT4 is the more recently identified receptor
Acamprosate D3 calcium ethyluracil EPZ-6438 was orally dosed toAcamprosate D3 calcium is the deuterium labeled Acamprosate calcium. Acamprosate calcium is a GABA receptor agonist and modulator of glutamatergic systems. Product information CAS Number: 1225580 94 8 Molecular Weight: 223. 30 Formula: C5H10CaNO4S Chemical Name: calcium 3 [(2,2,2 H)acetamido]propane 1 sulfonate Smiles: [Ca+2].[2H]C([2H])([2H])C(=O)NCCCS([O ])(=O)=O InChiKey: WPEXQWVYZZXPJW NIIDSAIPSA M InChi: InChI=1S C5H11NO4S. Ca c1 5(7)6 3 2 4
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