Chlorothricin elodipine Smiles: COC1=CC=C(C=C1)C1C=C(NC2=CC=NC(=N2)N2CCOCC2)ON=1

Smiles: COC1=CC=C(C=C1)C1C=C(NC2=CC=NC(=N2)N2CCOCC2)ON=1

Chemical Name: 7-phenyl-7-(2

Smiles: CCC/C=C1\OC(=O)C2[C@H](O)[C@@H](O)CCC=2\1

HC-070 blocks M2R-activated human TRPC1/TRPC4 channels with an IC50 of 1

CCC(=C(C1C=CC(O)=CC=1)C1C=CC(=CC=1)OCCNC)C1C=CC=CC=1

Chlorothricin elodipine Smiles: COC1=CC=C(C=C1)C1C=C(NC2=CC=NC(=N2)N2CCOCC2)ON=1IC50: 173, 500, 260, and 120 M for pyruvate carboxylases from Bacillus, Azotobacter, rat, and chicken, respectively. Chlorothricin is a macrolide type antibiotic. Macrolides, a class of natural products belonging to the polyketide class of natural products, consist of a large macrocyclic lactone ring. The lactone rings are oftem 14 , 15 , or 16 membered. Some macrolides have been reported to have antibiotic or antifungal activity and are widely used