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Go-6976 is a potent inhibitor of PKC in vitro (IC50 is 20 nM
26(2):278-288
(2012) Cancer Res
Flow cytometry is also performed to determine the expression marker Ki-67 in U2OS following 48 h treatment with DMSO or 10 uM JW74
Sachinidis A
Linifanib (ABT-869) - CAS# 796967-16-3 acin(DU 6859A) Go-6976 is a potent inhibitorLinifanib, CAS No. 796967 16 3, also known as ABT 869, is an orally bioavailable, small molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. Linifanib inhibits members of the vascular endothelial growth factor (VEGF) and platelet derived growth factor (PDGF) receptor families; it exhibits much less activity against unrelated RTKs, soluble tyrosine kinases, or serine threonine kinases. This agent does not have a
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