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InChi: InChI=1S/C27H37FO6/c1-5-6-7-23(33)34-27(22(32)15-29)16(2)12-20-19-9-8-17-13-18(30)10-11-24(17
Solubility: DMSO : 250 mg/mL (923
15-hexaene-3
24-72 hours) induces an increase of cell viability on MCF-7 cells mainly after 72 h of treatment whereas it is slightly cytotoxic on MDA-MB231 cells
InChiKey: CIRRFAQIWQFQSS-UHFFFAOYSA-N
ML-178 Catalog No.:M22300-C InChi: InChI=1S/C27H37FO6/c1-5-6-7-23(33)34-27(22(32)15-29)16(2)12-20-19-9-8-17-13-18(30)10-11-24(17ML 178 is a novel and selective S1P4 activator with EC50 value of 46. 3 nM . Sphingosine 1 phosphate (S1P) is an extracellular lipid mediator released by activated blood platelets that serves to influence heart rate, coronary artery caliber, endothelial integrity, lung epithelial integrity and lymphocyte recirculation through five of the S1P receptors (S1P1 EDG 1, S1P2 EDG 5, S1P3 EDG 3, S1P4 EDG 6, and S1P5 EDG 8). S1P4 receptor is coupled to Gi and