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is a potent TOPK (T-LAK cell-originated protein kinase) inhibitor
CAS Number: 1431699-67-0
and prostaglandin D2 (PGD2)
PHA-665752 significantly inhibits c-Met kinase activity with Ki of 4 nM
3-difluorotetracyclo[10
AM211 ide I is a potent TOPK (T-LAKAM211 is a potent, selective and orally bioavailable prostaglandin D2 (PGD2) receptor type 2 (DP2) antagonist, with IC50s of 4. 9 nM, 7. 8 nM, 4. 9 nM, 10. 4 nM for human, mouse, guinea pig, and rat DP2, respectively. Product information CAS Number: 1175526 27 8 Molecular Weight: 500. 51 Formula: C27H27F3N2O4 Chemical Name: 2 (2' {[(benzylcarbamoyl)(ethyl)amino]methyl} 6 methoxy 4' (trifluoromethyl) [1,1' biphenyl] 3 yl)acetic acid Smiles:
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