Y-27632 - Rock Inhibitor. CAS# 146986-50-7 60268 synthesis thereof and intermediates thereto

synthesis thereof and intermediates thereto

(2008) Mol Cancer Ther

and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2

CAS Number: 685898-44-6

It was identified by an imaging-based high throughput screening in human MSCs

Y-27632 - Rock Inhibitor. CAS# 146986-50-7 60268 synthesis thereof and intermediates theretoY 27632, CAS No. 146986 50 7, is a widely used, selective inhibitor of the Rho associated protein kinase p160ROCK with a Ki value at ~ 0. 14 M. In many studies, it was shown and used to enhance the survival and cloning efficiency of many primary cell types after single cell dissociation without affecting their self renewal properties, including hESC iPSCs, neural stem cells, intestinal stem cells, and mammary epithelial cells. Product information CAS